Eleanor Kellon, VMD
I don't know why the blasted notice isn't showing up, but I just put
up a new file:
File itself is called "Cushing's and Insulin Resistance Week 3
Appendix". It's an excerpt from the Cushing's and IR online course
that explains how all the blood/biochemical abnormalities can be
traced to one enzyme system.
Some background for those not taking the course:
Leptin - a hormone produced by fat cells. Horses with IR are also
resistant to leptin. Leptin normally turns off appetite and instructs
Adiponectin - another hormone produced by fat cells. Low in IR. It is
Adipokines = hormones/messengers produced by fat
Cytokines = cellular messengers (adipokines are a type of cytokine)
TNF-alpha - an inflammatory cytokine elevated in IR.