In a message dated 00-06-16 02:34:24 EDT, you write:

<< It took a fairly hefty dose to sedate him
followed by two more doses during the procedure >>

When my other (non-Cushings) horse had dental work done, I mentioned to the
vet that he weighted between 800 and 900 pounds. She had already drawn up the
dose but I imagine she guessed him about the same weight. However, once it
hit him, we had to prop him up against the wall because it hit him so hard. I
guess they react quite differently depending on body chemsitry?