GAIT study of knee arthritis: results application to equines?


After reading advice here about joint supplements for arthritis, I did a search of messages for discussion of the implications of the GAIT study.

Yahoo's search device doesn't allow two word searches, so I found nothing helpful.

Short version of the GAIT study:
-Participants taking the positive control, celecoxib, experienced statistically significant pain relief versus placebo—about 70 percent of those taking celecoxib had a 20 percent or greater reduction in pain versus about 60 percent for placebo.
Overall, there were no significant differences between the other treatments tested and placebo.
-For a subset of participants with moderate-to-severe pain, glucosamine combined with chondroitin sulfate provided statistically significant pain relief compared with placebo—about 79 percent had a 20 percent or greater reduction in pain versus about 54 percent for placebo. According to the researchers, because of the small size of this subgroup these findings should be considered preliminary and need to be confirmed in further studies.
-For participants in the mild pain subset, glucosamine and chondroitin sulfate together or alone did not provide statistically significant pain relief.
-glucosamine and chondroitin sulfate, together or alone, appeared to fare no better than placebo in slowing loss of cartilage

As Glucosamine + chondroitin showed some promise for pain relief for sufferers of moderate to severe pain (preliminary results), and glucosamine seems unsafe for IR equines, has there been a discussion here about the efficacy of chondroitin alone? Apologies if this is OT for this list.

Sonoma County, CA
Oct. 2012

Join to automatically receive all group messages.