Just my experience, my Frosty was having an ongoing uveitis attack and we couldn't get it under control. The vet suggested taking him off the 2 mg of pergolide and putting him on 1 mg prascend. Vet said he had seen wonderful results with it. I went ahead and put him on the prascend for about 5 months. I am sorry I did because I saw a dramatic drop in muscle tone in his topline and the rest of his body. I then went to put him back on the pergolide and it has been a battle with the pergolide veil to get him up to the 2 mgs he was on previously. The uveitis cleared up, but I am sure it wasn't because of the prascend.