My experience has been very good - using 2x a day at the rec'd doses (1) for horses who aren't sweating when weather turns warm in the Spring due to unusually warm winter -- after a few weeks, no longer need (2) horses needing antihistamines - esp. hydroxyzine/cetirizine for seasonal allergies that seem to stop them from sweating ... the antihist.s are usually needed April-Oct so they get ONE AC for the same period (3) an occasional horse who needs seasonally - don't know why but it works fine