Re: Increase Pergolide when?

Nancy C

Hi Kerry

Not sure we can say all horses will need or should taper up and/or down.  There are many who stay on one dose all year.  Because fall is the worst time for so many, dose increases happen frequently at that time, but many stay on that one increased dose all year.

Late summer into early fall is a critical time for careful monitoring of symptoms for all horses, but especially for those who have suffered laminitis before or who like mine, never have controlled insulin.

These two archived messages are helpful

Seasonal Rise When to Test ACTH Message by Eleanor


Increase Pergolide Message (Scale of Symptoms) by Patti

Want to also speak to the importance of understanding trim.

IMO and IME, during seasonal rise there is a need to be very vigilant with trim. All aspects of DDT+E are important.  Understanding the correct trim, making sure it is physiologically tight and balanced is a huge factor in whether a horse whose insulin is not controlled can withstand an insulin surge from slightly higher PPID issues (acth, cortisol) in the fall.  Or during spring shots and other events the IR horse is likely to experience.

We've got lots of resources to begin to understand trim on, both in the proceedings and on the  Laminitis and Trim pages there.  Will also be a big part of the  NO Laminitis! Conference in November. 

Nancy C in NH
ECIR Moderator 2003

NO Laminitis! 2015 in Georgetown, TX November 6-8: Dr. Eleanor Kellon, Dr. Robert Bowker, Dr. Philip Johnson, Dr. Benjamin Buchanan, Kathleen Gustafson, Daisy Bicking and Lavinia Fiscletti. Registration opening soon. Click on for updates.


---In EquineCushings@..., <kerry.isherwood@...> wrote :

So...PPID horses *will* need a pergolide increase during the rise? Is that the standard thinking? (Not asking how much; just that an increase is *usually* indicated)

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