Hi Susan,
It just so happens I was on the veterinary portal on Cornell's website this morning obtaining shipping lablels of my own, and yes, there is a way to send overnight To Cornell on a Friday for guaranteed Saturday delivery. So while that part of your equation may be true, and the sample DID arrive to Cornell on Saturday and was opened and stored correctly until the diagnostic part of lab opened again on Monday when theoretically your ACTH test was run, your disparate results from December and now raise serious flags. Perhaps the 104 was incorrect? Or does your horse have PPID symptoms that would support to very high 104 result?
Sorry that this doesn't help answer your question directly, but I wanted to demonstrate that the shipping Friday may be valid. Only a tracking slip would verify for sure when Cornell actually accepted the package (Saturday vs. Monday). If Monday, then definitely it sat all weekend with delivery carrier and your current results should not be considered valid, IMO.
Kerry(LVT) in NY
Sept 2014