I know Dr. Kellon and the group believe leptin testing is important. My vet, however, is not convinced, given the positive ACTH test and my horse's physical signs: crestiness, fat deposits over eyes and in front of shoulders. May I have the your thoughts on whether or not leptin testing is required for an already-diagnosed PPID horse? Also, my vet has stated that if I'm concerned about IR, she could prescribe Metformin which would help with IR. Thoughts?