Hi, i just found out about this page from Nora & Gary. I hope to be able to learn some new stuff and maybe share some of my experiences too. My 25 year old few spot leopard appaloosa gelding "Marvin" was diagnosed with cushings about 10 months ago. Since then he has been enroled in the Michigan State University Equine Cushings research study. In this program our bloodwork is done at no charge and the Permax he is on is discounted somewhat. In return MSU studies his progress thru reports provided by my vet. As far as I know this program is only open to those of us in Michigan. Marvin has steadily improved in some areas since he started taking the Permax. But he still has some problems like muscle wasting and hoof problems. ie Founder. But thanks to the naturalhorsetrim e-group founder Gretchen Fathauer's web site, he has been making progress with his hooves too. For those of you who are dealing with founder and laminitis you may want to check it out. Looking foreward to exchanging info and ideas, etc. Mary Goldy