Re: Logan Insulin increase
Eleanor Kellon, VMD
There are only 2 studies on this. The first from 1982 and a second in 2011 which hasn't actually been formally published. https://www.tapatalk.com/groups/thelaminitissite/acth-bioactive-v-immunoreactive-t19.html
They show that there are ACTH forms or ACTH-like substances in the pituitary of PPID horses that do not have the same hormonal activity but will cross-react on antibody based test assays.
This does NOT mean you can ignore the number. For one thing, the high number means that the pituitary intermediate lobe has uncontrolled output. It may not be all active ACTH but some certainly is and there are other active hormones being overproduced as well. It could explain why some horses are not as sick as we might expect them to be but it's not a reason to not treat because that high ACTH is a marker of the disease and how well, or not, it is controlled.
Eleanor in PA
www.drkellon.com 2 for 1 course sale