Ventral edema caused by Cushings?


Is there any literature that talks about the correlation of ventral edema and cushings? My pony developed ventral edema in the fall and a hardening crest, prompting me to increase her Prascend dose (now up to 2mg). After a couple of weeks, the ventral edema disappeared and her crest started to soften. Is this a coincidence? Or are there scientific studies that talk about this?

Also, can a horse be showing symptoms of Cushings (sweating, hard crest, ventral edema), and yet have normal ACTH and insulin levels? 

Helene A. in BC 2021
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