Date   

Re: wnv

fionn@...
 

Is Merial the same as Recombitek?  It looks like it to me, based on their website http://caribbean.merial.com/equine/Products/Pages/recombitek_wnv.aspx

I just googled Recombitek and got two that sell single doses.  I have not ever used either of these shops, so who knows how good they are but they do advertise single doses.



Michelle Peck Williams & Fionn
Lexington, Kentucky USA
Joined June 2012
fionn@...

Case history:  https://groups.yahoo.com/neo/groups/ECHistory5/files/Michelle%20Peck%20Williams/
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On Apr 26, 2015, at 6:50 PM, lj_friedman@... [EquineCushings] <EquineCushings@...> wrote:


are there any websites where we can order 1 or 2 of the merial wnv vaccine?  I see one site with a $70. minimum and other sites sell a box of 10 vaxes.  lj friedman san diego nov 2014



Re: wnv

Chanda
 

I didn't read all the details, but Chariton vet supply has single dose vials of Merial vaccine.  I don' t know what their shipping policy is.  Chariton Vet Supply

Chanda

MT 9/04


wnv

lj friedman
 

are there any websites where we can order 1 or 2 of the merial wnv vaccine?  I see one site with a $70. minimum and other sites sell a box of 10 vaxes.  lj friedman san diego nov 2014


Re: wnv vaccine

fionn@...
 

I’ve always given West Nile in May, right before Mosquito season.  I would think it would wear off too soon if you gave it in Nov.  And if you are giving them separately (as in not a 6-way), then I’d do it now.  Just my opinion and keep in mind I’m a history teacher, not a vet.

Michelle Peck Williams & Fionn
Lexington, Kentucky USA
Joined June 2012
fionn@...

Case history:  https://groups.yahoo.com/neo/groups/ECHistory5/files/Michelle%20Peck%20Williams/

Photo album: http://groups.yahoo.com/group/ECHistory5/photos/album/867903845/pic/list

Foot Photo album: http://groups.yahoo.com/group/ECHoof/photos/album/1767999070/pic/list


On Apr 26, 2015, at 1:58 PM, lj_friedman@... [EquineCushings] <EquineCushings@...> wrote:

thanks for the reply.. the reason I plan on doing wnv vax soon. bec of  mosquito season. is that the previous vets at a different barn vaxed everything yearly in November.. In my mind. this means that the wnv vax given in November of 2014, will offer little if any protection for the 2015 mosquito season.  thoughts?  lj friedman san diego nov 2014



Re: wnv vaccine

palomino.1982@...
 

I  order  the Recombitek WNV on line as local  (SD ) vets do not use modified live vax.

Susan
EC Primary Response
SO Cal 2007





Re: transporting cornell blood to the vet

palomino.1982@...
 

Just want to add that you do not want the blood to freeze...so make sure there is a layer of separation between ice and tubes of blood.  Or place in cup with water and a bit of ice to keep it chilled.  

I do my blood draws........and the first time ( being over zealous ) in wanting to keep it chilled...I froze it. That only happened once!

Susan
EC Primary Response
So Cal 2007


Re: transporting cornell blood to the vet

lj friedman
 

thanks for your reply.. with this attention to detail this will help me pass my vet tech exam.. ( just kidding) thanks again.. lj friedman san diego nov 2014

ECHistory8

 




Re: wnv vaccine

lj friedman
 

thanks for the reply.. the reason I plan on doing wnv vax soon. bec of  mosquito season. is that the previous vets at a different barn vaxed everything yearly in November.. In my mind. this means that the wnv vax given in November of 2014, will offer little if any protection for the 2015 mosquito season.  thoughts?  lj friedman san diego nov 2014


ECHistory8

 




Re: transporting cornell blood to the vet

Nancy C
 

Just want to add when I pull my own blood, I stand the tubes in a plastic cup in a cooler with ice for the trip to the clinic which is 90 mins away.

When I need to pull blood at  critical time, just before a holiday, have also had a small animal vet who's five minutes away from me, spin and separate.  Then I froze the tubes and delivered the following week.

Nancy C in NH
ECIR Moderator 2003
Learn the facts about IR, PPID, equine nutrition, exercise and the foot.
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---In EquineCushings@..., <kerry.isherwood@...> wrote :


Summary:
-Blood tubes need to be cooled, centrifuged, & separated within 4 hrs of drawing from horse. So unless yr vet brings his centrifuge with him (usually they do not) then yes, you should drive the blood tubes to vets office.
-Purple tops must be kept cool. These samples can be gently mixed or ride to the clinic on their sides; no big deal. They are not supposed to clot
-Red top tubes ARE supposed to form a clot on their own and ideally stand upright & remain undisturbed during transport. Its not a problem if the tubes fall over; they're going to be spun at a high rate of speed to separate the cells anyway so no real damage is done if the blood mixes/clot moves. You might see a remark about hemolysis in results (means some red blood cells ruptured but its not going to effect the leptin or insulin results; if you're running a blood chemistry to check on body-wide organ system function then possible hemolysis would potentially interfere with results). Best to keep the red tubes cooled also.

Im not going to get into the glucose part of the Cornell panel. If your vet is requesting the glucose test & you handle the blood tubes as Ive described above, the glucose results will be fairly accurate.

Kerry in NY
Licensed Vet Tech


Re: Increase prascend now? or wait

Eleanor Kellon, VMD
 




I would retest first.  Also consider requesting the front feet be blocked and if this causes improvement get radiographs.

Eleanor in PA
www.drkellon.com
EC Co-owner
Feb 2001



Re: wnv vaccine

 

The current standards for WNV vaccination is only once a year. Here are links:

Nancy Reed
Jazzi, 2013
San Diego County


Re: transporting cornell blood to the vet

Kerry Isherwood
 

LJ,

If you can drive it the vet's office, that would be ideal. Its not the refrigeration that is the critical step; its the separation of the blood's components by spinning the sample in a centrifuge that is. The separation has to be done no later than 4 hrs after blood is drawn from the horse. So, if your vet has add'l appts after yours, or gets an emergency call he/she must take, the blood wont get spun in time.

After spinning the tubes, the separated sections of blood have to be carefully extracted by hand and placed into a different type of blood tube and (ideally) frozen until shipment. All of this is delicate, tedious work that should be done within the 4-hr recommended window to have the most accurate results. So while refrigeration is important, its not the only part of the handling--the bulk of the work in prepping the blood sample happens in the vet's clinic, usually by his/her vet techs ;)

As for the initial transport of the tubes after drawing--the "purple tops" w the purple stopper have an additive that prevents the blood from clotting so you want the blood in those tubes to stay gently mixed together (ie, doesnt matter if theyre flat on side, standing up, etc). This is the sample for testing the ACTH (PPID status) and the one that must stay cooled.

Usually another tube is drawn with a red stopper; this one does not contain an anti-coagulant so the blood is supposed to form a big yucky clot in the bottom and a yellow liquid will separate itself out on top of the clot. Thats exactly what you want to happen. Yes, ideally, the tubes should stand upright but its not crucial for the results--you just dont want to disturb the clot in the tube once its formed (usually w/in 10 mins of draw) so if the tube accidentally falls on its side, no big deal, just leave it that way until you get to the vet's office. You should keep these red-top tubes chilled also but its not as critical as it is for the purple top tubes.

The red tops will be spun and serum will be extracted similarly to the purple tops.

Summary:
-Blood tubes need to be cooled, centrifuged, & separated within 4 hrs of drawing from horse. So unless yr vet brings his centrifuge with him (usually they do not) then yes, you should drive the blood tubes to vets office.
-Purple tops must be kept cool. These samples can be gently mixed or ride to the clinic on their sides; no big deal. They are not supposed to clot
-Red top tubes ARE supposed to form a clot on their own and ideally stand upright & remain undisturbed during transport. Its not a problem if the tubes fall over; they're going to be spun at a high rate of speed to separate the cells anyway so no real damage is done if the blood mixes/clot moves. You might see a remark about hemolysis in results (means some red blood cells ruptured but its not going to effect the leptin or insulin results; if you're running a blood chemistry to check on body-wide organ system function then possible hemolysis would potentially interfere with results). Best to keep the red tubes cooled also.

Im not going to get into the glucose part of the Cornell panel. If your vet is requesting the glucose test & you handle the blood tubes as Ive described above, the glucose results will be fairly accurate.

Kerry in NY
Licensed Vet Tech


Increase prascend now? or wait

lj friedman
 

I tired to post this message. not sure if it went thru .. With Jesse's discomfort possibly coming from acth not being properly controlled, I'm thinking of a treatment plan change.. Hoping Dr. Kellon can weigh in,

Current plan.  re-test acth for second time in the next week and increase prascend to 1.5 mg if levels arent in low to mid 20's, then re-test again in August..  ( march 03, 2015 ACTH cornell 40.7  ref 9-35.)


New thought:  Increase to 1.5mg prascend immediately. and look for signs of improvement..  and then retest at a later time?  not sure when exactly  I should re-test if I change treatment  plan to this?  


thanks  lj friedman san diego nov 2014


ECHistory8




transporting cornell blood to the vet

lj friedman
 

First time I did blood on Jesse, sent to Cornell, I drove the blood to the vets office for fast processing.. though they had a fridge on their truck. Was this overkill?  I also remember reading somewhere that the vials should be stood up as opposed to just lying on a car seat?  is this correct?   any other tips?  lj friedman san diego nov 2014


ECHistory8



wnv vaccine

lj friedman
 

In San Diego mosquito season is in full force  june -oct with peak aug to september. Dr.Kellon says to use the Merial recombitek vaccine.. She also says not to ignore eee/wee.  If eee/wee was given to Jesse in November, and wnv also was given in November, I'm thinking of giving wnv in the next week because the vet is coming out to draw cornell bloods.  Should I also consider eee/www in a few weeks to space this apart?  and is there an eee/wee vax brand that we prefer for our cushings horses?  lj friedman san dieo nov 2014


ECHistory8



Re: Mov-ease & Jherb

takarri@...
 


---In EquineCushings@..., <saragooch49@...> wrote :


Thank you to everyone for all the jherb and Move-Ease input.


Regarding the  protocol for administering jherb and Mov-Ease:  I  understand that both are supposed to be fed in a "small amount of feed"  on an empty stomach 20 minutes before the horse's other feed.


Hi Sara,

 

Whilst it’s desirable to administer J herb & ME as recommended, sometimes it’s not always possible. That’s life.  I used to make up the J in a syringe diluted with a bit of water and syringe it directly into the horses’ mouth, before going back and mixing up feeds. That gave me maybe 15 mins in between. Syringing was never an issue because they love J and looked upon it as a treat. Their stomachs were never truly empty as they had hay 24/7. By monitoring their gum colour and general demeanor, I was confident that they were getting the correct dose. The same goes for ME- though that was never considered a treat!  I had one on J herb and one on ME. Thankfully, my guys have always been good with syringing.  Alternatively, you can add J herb to the main feed; you just need to up the dose by 50%. Continue to monitor gum colour until you feel that you have reached the correct dose. I will assume that the same can be done with ME, but stand to be corrected.  If you can only dose once a day, so be it, but no need to give a stronger dose. As far as using a carrier, there’s no set weight, it’s usually as little as you can get away with the disguise what supplements you need to give.

 

Pauline & Spur

Sth West Vic

Australia Aug 07

EC Primary Response

http://tinyurl.com/7qbdyas

 

 


Re: Mov-ease & Jherb

Sara Gooch
 


Thank you to everyone for all the jherb and Move-Ease input.


Regarding the  protocol for administering jherb and Mov-Ease:  I  understand that both are supposed to be fed in a "small amount of feed"  on an empty stomach 20 minutes before the horse's other feed. I'm wondering if everyone does that?   And wondering...what's the maximum dry weight of carrier that can be used and still get the benefit from the jherb and ME? (One of my mares doesn't like the taste of Mov-Ease.)   Also if it's logistically nearly impossible to give the jherb and ME 20 minutes prior to other feed, is there any benefit to giving these supplements along with a main feeding?  One more question regarding jherb, is there any benefit to giving it once a day?  Maybe at a stronger dose? No?


Thanks in advance-- 

Sara, 2011, NE California

Nancy C in

 NH
ECIR Moderator 2003

FACT: Positive or negative changes to the foot accumulate over a period of months and years. See RM Bowker, VMD, PhD, The Vascular Cushion Of The Frog What Does It Do?  2013 NO Laminitis! Proceedings, Equine Cushing's and Insulin Resistance Group Inc.

 


Elevated Acth results

Julie Wood
 

I am just wondering if anyone can offer me some advice about elevated ACTH and the correct dosage of Pergolide. Following symptoms that his Cushings was not well controlled I had him re tested and my vet told me  his ACTH came back as 10.5 (I am still waiting for the complete test results to be emailed to me). My vet advised me to increase from .5mg to 1mg which I have done. How long should I leave it before retesting and what should his levels be. I am still in the process of completing his history sheet as I am waiting for information coming from 2 different vets. He is still a little sore in his feet but I seem to be able to control this with Bute and Previcox. Is there any other painkillers that I could try which works well with a laminitic horse?  I also have him in soft ride boots which seem to help with the hard ground.
Thank you in advance
Julie


Re: Metformin

beverly meyer
 

I read that Metformin reduced insulin, but only for 2 to 3 weeks before losing some efficacy.
I'd love to know if/when Cheripony sees ongoing results, and how to tell. My pony's insulin is always over 150. Although her fasting insulin last week was 43 when the vet ran "just ACTH".
Thanks,
Beverly 6/14
Beverly Texas


Re: Seasonal variations dopamine, cortisol and serotonin

Eleanor Kellon, VMD
 




Pergolide is important in December because PPID horses are abnormal all year long. There are times when they are worse, but never normal (with the exception of very early cases). December isn't terribly different from March, especially if you look at the standard deviation. The length of the vertical line above each data point corresponds to the standard deviation.  The differences between the groups only reach statistical significance for a few isolated time points at any time of year in this study. In other words, they overlap.  The most likely reason for this is that the control group actually contained one or more PPID horses, or vice versa, but that is assuming that plasma dopamine is a reliable diagnostic test and this has never been established. Dopamine is also produced by a variety of tissues outside the brain.

Eleanor in PA
www.drkellon.com
EC Co-owner
Feb 2001

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