There's the potential for prolactin to be at the root of all of this. Prolactin is under the control of dopamine just like the pituitary intermediate lobe hormones. Yes, you could try pergolide. The

Has anyone had any experience with Nutrizyme by AgriGro used in PPID/IR horses? Our stable manager is proposing to add it to all the horses feed to aid in fly control -- Barbara B 03/2013 Sedona,

We have to be aware of claims like "heightened awareness". How on earth could anyone tell that? It sounds like being picky but building on an assumption like that could take us in the wrong direction

I often wonder....although the word spooky probably isn't appropriate for my theory....if the behaviour described is more an indication of a horse who is feeling so much better,after a long time of

Thanks Dr Kellon. She is shifting her weight on all 4 now but don’t feel pulses. What will the Chaste tree berry do for her? Help with the ovarian issues or the buildup of prolactin. Is she ah big

Ah ok, thank you for clarifying. I did find a few articles that referenced 'hightened awareness' as a possible symptom but I wasn't sure if that translated to full on spooking. Thanks, Sherry and

Andrea, The easiest way to tell is to stop it for a few days if your vet agrees. The drug clears quickly. -- Eleanor in PA www.drkellon.com EC Owner 2001

Sherry, Elevated ACTH/cortisol won't cause spookiness but you may be thinking about discussions of large pituitary grows pressing on the optic nerve and causing vision problems. -- Eleanor in PA

Dr. Kellon, Couldn't "spookiness" or "over-reactivity" also be an indication that ACTH is still too high? I of course can't put my hands on a specific article so suffice to say uncontrolled PPID >

Yes, I had his eyes checked. Twice. By 2 different vets, once last March 2019 and at the end of Oct 2019 when he was "not quite right". Both times I was told his eyes were fine. As for the difference

I have had the same experience with my mare (19 this year). I have had her since she was a weanling and although she has always been high strung, she has never been spooky. She was somewhat quieter

Hi Kathie, So sorry to hear Target has had another set-back. If the farrier took off too much heel it could strain the DDFT, (deep digital flexor tendon), not the extensor tendon as that runs down the

Just one caveat here. If his calculator values are normal but he's not on pasture or grain when tested it would be wise to retest him about a week after getting pasture access to be sure he's doing

It could be but unlikely to show up after 2 months. How is this different from what you described as "frenetic" and "crazed" last spring? Have you had his eyes checked? Protein doesn't cause behavior

Hi Diana, I've added a couple of mark-ups to Prince's album: https://ecir.groups.io/g/CaseHistory/album?id=242061 Biggest issue is that the toes are too long horizontally at ground level, pushing the

Please don’t give up on Target it sounds like you are so close to the turning point. As someone more expert than I has already said, do get xrays and then get mark-ups done by Lavinia so that you

Definitely try stopping the estradiol. I can't explain how it could make her worse but it isn't helping. I'm wondering if there is prolactin overproduction? Prolactinoma could be her issue although

Hello, ok so I gave her 6mg of estradiol this am. Before I gave her the estradiol she was walking good with boots and and even with boots off she walking around well. Her crest was down a bit as was

Hi Chuan, Two other possibilities to add to Cass' observations. Her RH is the one with the negative plane coffin bone, so that could be contributing to her looking like she is more "off" on the LF. If

-- Heather August 5, 2017, Brandon, Manitoba, Canada Riosa Case History https://ecir.groups.io/g/CaseHistory/files/Heather%20and%20Riosa