Re: Vinegar for insulin/glucose regulation
Sherry Morse
Hi Kristen, Not sure if you searched the archives, but you may have missed this note from Nancy last December: https://ecir.groups.io/g/main/message/245150 Cinnamon was trialed here years ago and while popular due to human meds,
has not been found to work in horses. ECIR has not routinely
recommended it for at least a decade. From our files: Cinnamon is no longer routinely recommended. It had been hoped to improve insulin sensitivity, but instead it may lower blood sugar (glucose) without lowering insulin levels. Since most IR horses have glucose in the normal ranges, cinnamon sometimes lowers it too much. For that reason, the ECIR Group doesn't use it routinely. If you have a horse that is a true diabetic - high glucose - then cinnamon may be helpful. -- Nancy C in NH ECIR Moderator 2003 ECIR Group Inc. President/Treasurer 2019-2020 And from Dr. Kellon last July:https://ecir.groups.io/g/main/message/237865 Some horses like the taste and it is a good antioxidant but the
metabolic effects seen in humans have not panned out in horses.
Specifically, we saw more of a tendency to lower glucose than have an
effect on insulin. In other species it reduces stomach acid, stomach
gas. No equine research. No loose droppings research. -- Eleanor in PA www.drkellon.com
Thanks, Sherry and Scutch (and Scarlet over the bridge) EC Primary Response PA 2014 https://ecir.groups.io/g/CaseHistory/files/Sherry%20and%20Scutch_Scarlet https://ecir.groups.io/g/CaseHistory/album?id=78891
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Re: Vinegar for insulin/glucose regulation
Hi Kirsten.
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Re: Suspected IR but blood results suggest otherwise
Sherry Morse
Speedibeet (dry): https://ecir.groups.io/g/main/files/9c%20Analyses%20of%20Various%20Feeds/1.%20Beet%20Pulp/SpeediBeetDry.pdf Rinsed/soaked/rinsed brings the iron down quite significantly: https://ecir.groups.io/g/main/files/9c%20Analyses%20of%20Various%20Feeds/1.%20Beet%20Pulp/Speedi%20Beet%20RSR.pdf
Thanks, Sherry and Scutch (and Scarlet over the bridge) EC Primary Response PA 2014 https://ecir.groups.io/g/CaseHistory/files/Sherry%20and%20Scutch_Scarlet https://ecir.groups.io/g/CaseHistory/album?id=78891
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Re: Donkey!!!
Sherry Morse
Hi Kelsey, All of those feeds, and most commercial feeds, are higher in ESC+starch than the 10% we recommend which is why we suggest using ODTBC or beet pulp as a carrier. Triple Crown Complete is also not safe for an IR equine and has even higher levels of ESC+starch than the senior - again you can reference that file I just mentioned, as well as this slightly older list: https://ecir.groups.io/g/main/files/9c%20Analyses%20of%20Various%20Feeds/Triple%20Crown%20Products/Triple%20Crown%20Horse%20Feeds%202005-05-13.pdf You may also want to test for Ehrlichia as that may also cause a fever with apparent laminitis. If he's in acute pain that can throw off the insulin and ACTH readings so just something to keep in mind about trying to do bloodwork at this point.
Thanks, Sherry and Scutch (and Scarlet over the bridge) EC Primary Response PA 2014 https://ecir.groups.io/g/CaseHistory/files/Sherry%20and%20Scutch_Scarlet https://ecir.groups.io/g/CaseHistory/album?id=78891
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Re: Dietary effect on insulin and glucose: instant or cumulative?
hmfox77@...
Such good questions! I'll be following this to see what the experts have to say.
Now that I'm on this IR ride I've been wondering if I'll ever be able to leave home again. Even the thought of being away for 1 night gives me the vapors! I think finding hay under 10% would calm my nerves somewhat, but I'm having trouble doing that so I worry that if I didn't soak for a day things would fall apart quickly. -- Heather F Minnesota 2020 https://ecir.groups.io/g/CaseHistory/files/Heather%20and%20Ty https://ecir.groups.io/g/CaseHistory/album?id=248884&p=Created,,,20,2,0,0
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Re: Suspected IR but blood results suggest otherwise
Hi Emma,
I couldn't find iron levels for Speedi-Beet or Kwik Beet, but many members use Speedi-Beet without issue. Maybe your trimmer has equine nutrition background, though, and has the skinny. Do you know the iron levels for each? In any case,we do recommend rinsing,soaking,and rinsing beet pulp,for best results with our compromised horses. Going to case history now. Thanks for changing the links! -- Lorna in Eastern Ontario
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Re: Suspected IR but blood results suggest otherwise
emma@...
Thank you all. LInks should be live now. I will update photos later this evening. Tom has been trimmed since the last x-rays were taken. My trimmer and I have discussed boots but as he is comfortable walking on tarmac we have decided not to boot him as the trimmer suggests this will be better for the foot and sole development. He is currently walking out freely with no sign of discomfort.
2019 bloods. These were taken pm. His last meal would have been about 7am (Happy Hoof). His hay was soaked. He would have finished his hay by midday. Karo syrup test. This was taken am. His last meal would have been the morning before and he had hay overnight (not soaked) but this would have all gone before midnight probably (sorry it was a long time ago and my notes aren't that detailed). 2020 bloods. Bloods were taken around 4-5pm. His last meal (beet pulp etc) was at 9am. He then had an "easy to eat" haynet which he usually finishes by about 12pm. He still had hay in a trickle net up until when the bloods were taken. This was the same for the Karo syrup test too. I haven't had the hay tested as supplier keeps changing - not ideal but the hay is provided by the yard. I am not rinsing the sugar beet at the moment. It is the quick soak beet (ready in 10 mins). I was using Speedibeet but my trimmer said to move to Kwik Beet which is lower in iron. Have been mixing the two but only a day or two left of the speedibeet. Thanks Emma -- Emma M in East Sussex, UK 2020 Case History for Tom: https://ecir.groups.io/g/CaseHistory/files/Emma and Tom Photo Album for Tom: https://ecir.groups.io/g/CaseHistory/album?id=249458
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Re: Donkey!!!
Cindy, thank you so much for all the info!! 1800 fever of 102.6 he is still off quite a bit in the front feet but better than yesterday (he’s also was on Banamine and previous was only on bute) the strange thing is there is no digital pulse and no heat in the feet. I even have a temp gun, his feet are the same temp as his old pony friend.
As soon as I am home to my computer, I will work on his case study.
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Re: Acute Laminitis / Hay Analysis / Bloodwork
The ODTB cubes are balanced to themselves so that if they were the only source of feed then only salt, flax and vit E need to be added. If they are not the only feed in your horse's diet, the additional hay or feed will require mineral balancing and supplementation. The ODTB cubes will not add any minerals that you need to balance your hay. So yes, if you are also feeding hay you will need to add minerals. If you have a hay test with major and trace minerals, it's well worth paying a balancer to find the most appropriate mineral mix out there, or have them design a custom supplement for your hay.
-- Kirsten and Shaku (IR) - 2019 Kitimat, BC, Canada ECIR Group Moderator Shaku's Photo Album
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Re: Vinegar for insulin/glucose regulation
Thanks Nancy! So is it the official position of ECIR that vinegar does not have the same effect in horses that it does in people? Or do you think Beau was so iron overloaded that nothing would help?
For cinnamon, I believe the effect is on glucose, not insulin, and that it's important to note that the effect on glucose is seen from the much cheaper and more widely available "cassia" cinnamon. But "cassia" cinnamon, also known as Chinese cinnamon—or probably what you’re getting at the store, if it just says cinnamon—contains a compound called coumarin, which may be toxic to the liver in high enough doses." Ceylon or vernum cinnamon doesn't have the toxin, but neither does it have the effect on blood sugar in humans. -- Kirsten and Shaku (IR) - 2019 Kitimat, BC, Canada ECIR Group Moderator Shaku's Photo Album
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Dietary effect on insulin and glucose: instant or cumulative?
I know dietary changes have an immediate effect on lowering insulin, but is there a cumulative effect seen over time as well? For example, I've been soaking hay for about 6 weeks now. If I continue to soak, could his insulin get progressively lower? And, if I stopped soaking tomorrow (ie, if I went away for a week and didn't have anyone to soak hay for him) would Shaku's insulin go right back to where it was before I started soaking hay, or would it jump up partway then climb more slowly back to where it was? And if insulin didn't rebound all the way immediately, how long would it take to return to his 'unsoaked hay' baseline? What about glucose?
----- Kirsten and Shaku (IR) - 2019 Kitimat, BC, Canada ECIR Group Moderator Shaku's Photo Album
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Re: Vinegar for insulin/glucose regulation
You do know that’s not correct. unfed horses do not give you correct insulin levels.
-- LJ Friedman Nov 2014 Vista, Northern San Diego, CA Jesse and majestic ‘s Case History
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Re: Donkey!!!
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Re: Vinegar for insulin/glucose regulation
Hi Kirsten and all --
I've had some experience with my diabetic and very high insulin boy Beau before he passed. I was feeding 1 cup 2xs per day. We were doing this to help jump start his mineral absorption. No matter what form and how much Mag we gave him, he did not absorb well. To me this was a big piece of the puzzle as to why we could not bring his hyperinsulinemia under control. We never saw a change in insulin and glucose with adding 2 cups of vinegar per day. His diet was squeaky clean; his PPID under control: he was iron overloaded. In addition, to speak to Clare's question -- Cinnamon did not have effect either. This is true not only for my horse when he was diabetic, but also majority of horses on ECIR who have tried it. -- Nancy C in NH ECIR Moderator 2003 ECIR Group Inc. President/Treasurer 2019-2020 Join us at the 2021 NO Laminitis! Conference, August 12-15, Harrisburg, PA
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Re: Acute Laminitis / Hay Analysis / Bloodwork
Michele Goldberg <ladipus@...>
Ok ...so do you still add stuff like minerals or a forage Balencer to your Ontario Dehy Timothy Balance Cubes/Stabul One mixture?? I’m guessing I would still need to add something like a balancer to my ODTB cubes since I’m only feeding a small amount of it to achieve proper nutritional requirements ?? I was considering trying the Vermont Blend and mixing with the ODTB cubes ?? -- Michele Goldberg Bernville, Pa joined 5/19/2016
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Re: Vinegar for insulin/glucose regulation
Clare Summers
The vet wanted the insulin result without any raise from feed, that’s how she’s always had her levels checked.
-- Clare in NS, Canada 2020 Cory; IR/EMS 2000 ASB mare
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Welcome Letter for Clare in NS Canada, was previously Re: Vinegar for insulin/glucose regulation
Hi Clare
Have you started your Case History? If you haven't done so yet, please join our case history sub-group. We appreciate you following the uploading instructions so your folder is properly set up with the documents inside. Go to this CH message with info on how to use various devices and forms. If you have any trouble, just post a message to let us know where you are stuck. Orienting information, such as how the different ECIR sections relate to each other, message etiquette, what goes where and many how-to pages are in the Wiki. There is also an FAQs on our website that will help answer the most common and important questions new members have. Below is a general summary of our DDT/E philosophy which is short for Diagnosis, Diet, Trim and Exercise.
DIAGNOSIS: There are two conditions dealt with here: Cushings (PPID) and Insulin Resistance (IR). These are two separate issues that share some overlapping symptoms. An equine may be either PPID or IR, neither or both. While increasing age is the greatest risk factor for developing PPID, IR can appear at any age and may have a genetic component. Blood work is used for diagnosis as well as monitoring the level of control of each. PPID is diagnosed using the Endogenous ACTH test, while IR is diagnosed by testing non-fasting insulin, glucose and Leptin. Leptin is the hormone that says "stop eating". Knowing this helps to differentiate if a horse is IR "at baseline" or if an elevated ACTH is "driving" the insulin up. In Europe, substitute adiponectin for the leptin test. *Before calling your vet to draw blood for tests, we suggest saving time and wasted money by reading these details and then sharing them with your vet so that everyone is on the same page regarding correct testing and protocols. *Please remember to request copies of the results of all the tests done rather than just relying on verbal information. Your vet should be able to email these to you. If you have previous test results, please include those as well. All should go in your CH, but if you are having any trouble with the CH, just post in the messages for now. Treatment: IR is a metabolic type - not a disease - that is managed with a low sugar+starch diet and exercise (as able). The super-efficient easy keeper type breeds such as minis, ponies, Morgans, Arabs, Rockies are some of the classic examples. PPID is a progressive disease that is treated with the medication pergolide. Some, but not all, individuals may experience a temporary loss of appetite, lethargy and/or depression when first starting the medication. To avoid this "pergolide veil" (scroll down for side effects), we recommend weaning onto the drug slowly and the use of the product APF. The best long term results are seen when the ACTH is maintained in the middle of the normal range at all times, including during the annual seasonal rise. To accomplish this, the amount of medication may need to increase over time. Neither condition is ever "cured", only properly controlled for the remainder of the equine's life. If your partner is both PPID and IR then both medication and diet management will be needed. DIET: Almost all commercial feeds are not suitable - no matter what it says on the bag. Please see the International Safe Feeds List for the safest suggestions. No hay is "safe" until proven so by chemical analysis. The diet that works for IR is:
We use grass hay, tested to be under 10% ESC + starch, with minerals added to balance the excesses and deficiencies in the hay, plus salt, and to replace the fragile ingredients that are lost when grass is cured into hay, we add ground flax seed and Vitamin E. This diet is crucial for an IR horse, but also supports the delicate immune system of a PPID horse. *Until you can get your hay tested and balanced we recommend that you soak your hay and use the emergency diet (scroll down for it). The emergency diet is not intended for long term use, but addresses some of the most common major deficiencies. Testing your hay and getting the minerals balanced to its excesses and deficiencies is the best way to feed any equine. If you absolutely cannot test your hay and balance the minerals to it, or would like to use a "stop gap" product until you get your hay balanced, here's a list of "acceptable" ration balancers. There is a lot of helpful information in the start here folder so it is important you read all the documents found there. The emergency diet involves soaking your untested hay for an hour in cold water or 30 minutes in hot water. This removes up to 30% of the sugar content, but no starch. Starch is worse than sugar since it converts 100% to glucose while sugar only converts 50%, so starch causes a bigger insulin spike. Make sure you dump the soaking water where the equine(s) can't get to it. What you don't feed on the IR diet is every bit as, if not more important than, what you do feed! No grass. No grain. No sugary treats, including apples and carrots. No brown/red salt blocks which contain iron (and sometimes molasses) which interferes with mineral balancing, so white salt blocks only. No products containing molasses. No bagged feeds with a combined sugar and starch of over 10% or starch over about 4%, or fat over about 4%. Unfortunately, even bagged feeds that say they are designed for IR and/or PPID equines are usually too high in sugar, starch and/or fat. It’s really important to know the actual analysis and not be fooled by a name that says it is suitable for IR/PPID individuals. We do not recommend feeding alfalfa hay to IR/PPID equines as it makes many of them laminitic. Although it tends to be low in sugar, many times the starch is higher and does not soak out. Additionally, protein and calcium are quite high, which can contribute to sore footedness and make mineral balancing very difficult. TRIM: A proper trim is toes backed and heels lowered so that the hoof capsule closely hugs and supports the internal structures of the foot. Though important for all equines, it's essential for IR and/or PPID equines to have a proper trim in place since they are at increased risk for laminitis. After any potential triggers are removed from the diet, and in PPID individuals, the ACTH is under control, the realigning trim is often the missing link in getting a laminitic equine comfortable. In general, laminitic hooves require more frequent trim adjustments to maintain the proper alignment so we recommend the use of padded boots rather than fixed appliances (i.e. shoes, clogs), at least during the initial phases of treatment. Sometimes subclinical laminitis can be misdiagnosed as arthritis, navicular, or a host of other problems as the animal attempts to compensate for sore feet. You are encouraged to make an album and post hoof pictures and any radiographs you might have so we can to look to see if you have an optimal trim in place. Read this section of the wiki for how to get a hoof evaluation, what photos are needed, and how to get the best hoof shots and radiographs. EXERCISE: The best IR buster there is, but only if the equine is comfortable and non-laminitic. An individual that has had laminitis needs 6-9 months of correct realigning trims before any serious exercise can begin. Once the equine is moving around comfortably at liberty, hand walking can begin in long straight lines with no tight turns. Do not force a laminitic individual to move, or allow its other companions to do so. It will begin to move once the pain begins to subside. Resting its fragile feet is needed for healing to take place so if the animal wants to lay down, do not encourage it to get up. Place feed and water where it can be reached easily without having to move any more than necessary. Be extremely careful about movement while using NSAIDs (bute, banamine, previcox, etc.) as it masks pain and encourages more movement than these fragile feet are actually able to withstand. Additionally, NSAIDs (and icing) do not work on metabolic laminitis and long term NSAID use interferes with healing. Therefore, we recommend tapering off NSAIDs after the first week or so of use. If after a week's time your equine's comfort level has not increased, then the cause of the laminitis has not been removed and keeping up the NSAIDs isn't the answer - you need to address the underlying cause.
There is lots more information in our files and archived messages and also on our website. It is a lot of information, so take some time to go over it and feel free to ask any questions. If you are feeling overwhelmed, don't worry, you will catch on, and we are always here to help you! Once you have your case history uploaded, we can help you help your equine partner even better. For members outside North America, there are country specific folders in the files and many international lists in the wiki to help you find local resources. If you have any technical difficulties, please let us know so we can help you. -- Cindy and Glow - Sep 2017, Singapore
ECIR Primary Response Case History: https://ecir.groups.io/g/CaseHistory/files/Cindy%20and%20Glow
Photos: https://ecir.groups.io/g/CaseHistory/album?id=9798
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Re: Hay Analysis only lists sugar
hmfox77@...
Thank you Sherry! The abbreviations are a real hoot. I confused myself when I was writing my post LOL. That's all I really wanted to know, if it was IR safe.
-- Heather F Minnesota 2020 https://ecir.groups.io/g/CaseHistory/files/Heather%20and%20Ty https://ecir.groups.io/g/CaseHistory/album?id=248884&p=Created,,,20,2,0,0
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Re: Donkey!!!
Cindy Q
Dear Kelsey
Have you started your Case History? If you haven't done so yet, please join our case history sub-group. We appreciate you following the uploading instructions so your folder is properly set up with the documents inside. Go to this CH message with info on how to use various devices and forms. If you have any trouble, just post a message to let us know where you are stuck. Orienting information, such as how the different ECIR sections relate to each other, message etiquette, what goes where and many how-to pages are in the Wiki. There is also an FAQs on our website that will help answer the most common and important questions new members have. Below is a general summary of our DDT/E philosophy which is short for Diagnosis, Diet, Trim and Exercise.
DIAGNOSIS: There are two conditions dealt with here: Cushings (PPID) and Insulin Resistance (IR). These are two separate issues that share some overlapping symptoms. An equine may be either PPID or IR, neither or both. While increasing age is the greatest risk factor for developing PPID, IR can appear at any age and may have a genetic component. Blood work is used for diagnosis as well as monitoring the level of control of each. PPID is diagnosed using the Endogenous ACTH test, while IR is diagnosed by testing non-fasting insulin, glucose and Leptin. Leptin is the hormone that says "stop eating". Knowing this helps to differentiate if a horse is IR "at baseline" or if an elevated ACTH is "driving" the insulin up. In Europe, substitute adiponectin for the leptin test. *Before calling your vet to draw blood for tests, we suggest saving time and wasted money by reading these details and then sharing them with your vet so that everyone is on the same page regarding correct testing and protocols. *Please remember to request copies of the results of all the tests done rather than just relying on verbal information. Your vet should be able to email these to you. If you have previous test results, please include those as well. All should go in your CH, but if you are having any trouble with the CH, just post in the messages for now. Treatment: IR is a metabolic type - not a disease - that is managed with a low sugar+starch diet and exercise (as able). The super-efficient easy keeper type breeds such as minis, ponies, Morgans, Arabs, Rockies are some of the classic examples. PPID is a progressive disease that is treated with the medication pergolide. Some, but not all, individuals may experience a temporary loss of appetite, lethargy and/or depression when first starting the medication. To avoid this "pergolide veil" (scroll down for side effects), we recommend weaning onto the drug slowly and the use of the product APF. The best long term results are seen when the ACTH is maintained in the middle of the normal range at all times, including during the annual seasonal rise. To accomplish this, the amount of medication may need to increase over time. Neither condition is ever "cured", only properly controlled for the remainder of the equine's life. If your partner is both PPID and IR then both medication and diet management will be needed. DIET: Almost all commercial feeds are not suitable - no matter what it says on the bag. Please see the International Safe Feeds List for the safest suggestions. No hay is "safe" until proven so by chemical analysis. The diet that works for IR is:
We use grass hay, tested to be under 10% ESC + starch, with minerals added to balance the excesses and deficiencies in the hay, plus salt, and to replace the fragile ingredients that are lost when grass is cured into hay, we add ground flax seed and Vitamin E. This diet is crucial for an IR horse, but also supports the delicate immune system of a PPID horse. *Until you can get your hay tested and balanced we recommend that you soak your hay and use the emergency diet (scroll down for it). The emergency diet is not intended for long term use, but addresses some of the most common major deficiencies. Testing your hay and getting the minerals balanced to its excesses and deficiencies is the best way to feed any equine. If you absolutely cannot test your hay and balance the minerals to it, or would like to use a "stop gap" product until you get your hay balanced, here's a list of "acceptable" ration balancers. There is a lot of helpful information in the start here folder so it is important you read all the documents found there. The emergency diet involves soaking your untested hay for an hour in cold water or 30 minutes in hot water. This removes up to 30% of the sugar content, but no starch. Starch is worse than sugar since it converts 100% to glucose while sugar only converts 50%, so starch causes a bigger insulin spike. Make sure you dump the soaking water where the equine(s) can't get to it. What you don't feed on the IR diet is every bit as, if not more important than, what you do feed! No grass. No grain. No sugary treats, including apples and carrots. No brown/red salt blocks which contain iron (and sometimes molasses) which interferes with mineral balancing, so white salt blocks only. No products containing molasses. No bagged feeds with a combined sugar and starch of over 10% or starch over about 4%, or fat over about 4%. Unfortunately, even bagged feeds that say they are designed for IR and/or PPID equines are usually too high in sugar, starch and/or fat. It’s really important to know the actual analysis and not be fooled by a name that says it is suitable for IR/PPID individuals. We do not recommend feeding alfalfa hay to IR/PPID equines as it makes many of them laminitic. Although it tends to be low in sugar, many times the starch is higher and does not soak out. Additionally, protein and calcium are quite high, which can contribute to sore footedness and make mineral balancing very difficult. TRIM: A proper trim is toes backed and heels lowered so that the hoof capsule closely hugs and supports the internal structures of the foot. Though important for all equines, it's essential for IR and/or PPID equines to have a proper trim in place since they are at increased risk for laminitis. After any potential triggers are removed from the diet, and in PPID individuals, the ACTH is under control, the realigning trim is often the missing link in getting a laminitic equine comfortable. In general, laminitic hooves require more frequent trim adjustments to maintain the proper alignment so we recommend the use of padded boots rather than fixed appliances (i.e. shoes, clogs), at least during the initial phases of treatment. Sometimes subclinical laminitis can be misdiagnosed as arthritis, navicular, or a host of other problems as the animal attempts to compensate for sore feet. You are encouraged to make an album and post hoof pictures and any radiographs you might have so we can to look to see if you have an optimal trim in place. Read this section of the wiki for how to get a hoof evaluation, what photos are needed, and how to get the best hoof shots and radiographs. EXERCISE: The best IR buster there is, but only if the equine is comfortable and non-laminitic. An individual that has had laminitis needs 6-9 months of correct realigning trims before any serious exercise can begin. Once the equine is moving around comfortably at liberty, hand walking can begin in long straight lines with no tight turns. Do not force a laminitic individual to move, or allow its other companions to do so. It will begin to move once the pain begins to subside. Resting its fragile feet is needed for healing to take place so if the animal wants to lay down, do not encourage it to get up. Place feed and water where it can be reached easily without having to move any more than necessary. Be extremely careful about movement while using NSAIDs (bute, banamine, previcox, etc.) as it masks pain and encourages more movement than these fragile feet are actually able to withstand. Additionally, NSAIDs (and icing) do not work on metabolic laminitis and long term NSAID use interferes with healing. Therefore, we recommend tapering off NSAIDs after the first week or so of use. If after a week's time your equine's comfort level has not increased, then the cause of the laminitis has not been removed and keeping up the NSAIDs isn't the answer - you need to address the underlying cause.
There is lots more information in our files and archived messages and also on our website. It is a lot of information, so take some time to go over it and feel free to ask any questions. If you are feeling overwhelmed, don't worry, you will catch on, and we are always here to help you! Once you have your case history uploaded, we can help you help your equine partner even better. For members outside North America, there are country specific folders in the files and many international lists in the wiki to help you find local resources. If you have any technical difficulties, please let us know so we can help you. -- Cindy and Glow - Sep 2017, Singapore
ECIR Primary Response Case History: https://ecir.groups.io/g/CaseHistory/files/Cindy%20and%20Glow
Photos: https://ecir.groups.io/g/CaseHistory/album?id=9798
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Re: Suspected IR but blood results suggest otherwise
Cindy Q
Hi Emma
Welcome to the group! Thank you for filling up your CH and uploading your rads. Have you started your Case History? If you haven't done so yet, please join our case history sub-group. We appreciate you following the uploading instructions so your folder is properly set up with the documents inside. Go to this CH message with info on how to use various devices and forms. If you have any trouble, just post a message to let us know where you are stuck. Orienting information, such as how the different ECIR sections relate to each other, message etiquette, what goes where and many how-to pages are in the Wiki. There is also an FAQs on our website that will help answer the most common and important questions new members have. Below is a general summary of our DDT/E philosophy which is short for Diagnosis, Diet, Trim and Exercise.
DIAGNOSIS: There are two conditions dealt with here: Cushings (PPID) and Insulin Resistance (IR). These are two separate issues that share some overlapping symptoms. An equine may be either PPID or IR, neither or both. While increasing age is the greatest risk factor for developing PPID, IR can appear at any age and may have a genetic component. Blood work is used for diagnosis as well as monitoring the level of control of each. PPID is diagnosed using the Endogenous ACTH test, while IR is diagnosed by testing non-fasting insulin, glucose and Leptin. Leptin is the hormone that says "stop eating". Knowing this helps to differentiate if a horse is IR "at baseline" or if an elevated ACTH is "driving" the insulin up. In Europe, substitute adiponectin for the leptin test. *Before calling your vet to draw blood for tests, we suggest saving time and wasted money by reading these details and then sharing them with your vet so that everyone is on the same page regarding correct testing and protocols. *Please remember to request copies of the results of all the tests done rather than just relying on verbal information. Your vet should be able to email these to you. If you have previous test results, please include those as well. All should go in your CH, but if you are having any trouble with the CH, just post in the messages for now. Treatment: IR is a metabolic type - not a disease - that is managed with a low sugar+starch diet and exercise (as able). The super-efficient easy keeper type breeds such as minis, ponies, Morgans, Arabs, Rockies are some of the classic examples. PPID is a progressive disease that is treated with the medication pergolide. Some, but not all, individuals may experience a temporary loss of appetite, lethargy and/or depression when first starting the medication. To avoid this "pergolide veil" (scroll down for side effects), we recommend weaning onto the drug slowly and the use of the product APF. The best long term results are seen when the ACTH is maintained in the middle of the normal range at all times, including during the annual seasonal rise. To accomplish this, the amount of medication may need to increase over time. Neither condition is ever "cured", only properly controlled for the remainder of the equine's life. If your partner is both PPID and IR then both medication and diet management will be needed. DIET: Almost all commercial feeds are not suitable - no matter what it says on the bag. Please see the International Safe Feeds List for the safest suggestions. No hay is "safe" until proven so by chemical analysis. The diet that works for IR is:
We use grass hay, tested to be under 10% ESC + starch, with minerals added to balance the excesses and deficiencies in the hay, plus salt, and to replace the fragile ingredients that are lost when grass is cured into hay, we add ground flax seed and Vitamin E. This diet is crucial for an IR horse, but also supports the delicate immune system of a PPID horse. *Until you can get your hay tested and balanced we recommend that you soak your hay and use the emergency diet (scroll down for it). The emergency diet is not intended for long term use, but addresses some of the most common major deficiencies. Testing your hay and getting the minerals balanced to its excesses and deficiencies is the best way to feed any equine. If you absolutely cannot test your hay and balance the minerals to it, or would like to use a "stop gap" product until you get your hay balanced, here's a list of "acceptable" ration balancers. There is a lot of helpful information in the start here folder so it is important you read all the documents found there. The emergency diet involves soaking your untested hay for an hour in cold water or 30 minutes in hot water. This removes up to 30% of the sugar content, but no starch. Starch is worse than sugar since it converts 100% to glucose while sugar only converts 50%, so starch causes a bigger insulin spike. Make sure you dump the soaking water where the equine(s) can't get to it. What you don't feed on the IR diet is every bit as, if not more important than, what you do feed! No grass. No grain. No sugary treats, including apples and carrots. No brown/red salt blocks which contain iron (and sometimes molasses) which interferes with mineral balancing, so white salt blocks only. No products containing molasses. No bagged feeds with a combined sugar and starch of over 10% or starch over about 4%, or fat over about 4%. Unfortunately, even bagged feeds that say they are designed for IR and/or PPID equines are usually too high in sugar, starch and/or fat. It’s really important to know the actual analysis and not be fooled by a name that says it is suitable for IR/PPID individuals. We do not recommend feeding alfalfa hay to IR/PPID equines as it makes many of them laminitic. Although it tends to be low in sugar, many times the starch is higher and does not soak out. Additionally, protein and calcium are quite high, which can contribute to sore footedness and make mineral balancing very difficult. TRIM: A proper trim is toes backed and heels lowered so that the hoof capsule closely hugs and supports the internal structures of the foot. Though important for all equines, it's essential for IR and/or PPID equines to have a proper trim in place since they are at increased risk for laminitis. After any potential triggers are removed from the diet, and in PPID individuals, the ACTH is under control, the realigning trim is often the missing link in getting a laminitic equine comfortable. In general, laminitic hooves require more frequent trim adjustments to maintain the proper alignment so we recommend the use of padded boots rather than fixed appliances (i.e. shoes, clogs), at least during the initial phases of treatment. Sometimes subclinical laminitis can be misdiagnosed as arthritis, navicular, or a host of other problems as the animal attempts to compensate for sore feet. You are encouraged to make an album and post hoof pictures and any radiographs you might have so we can to look to see if you have an optimal trim in place. Read this section of the wiki for how to get a hoof evaluation, what photos are needed, and how to get the best hoof shots and radiographs. EXERCISE: The best IR buster there is, but only if the equine is comfortable and non-laminitic. An individual that has had laminitis needs 6-9 months of correct realigning trims before any serious exercise can begin. Once the equine is moving around comfortably at liberty, hand walking can begin in long straight lines with no tight turns. Do not force a laminitic individual to move, or allow its other companions to do so. It will begin to move once the pain begins to subside. Resting its fragile feet is needed for healing to take place so if the animal wants to lay down, do not encourage it to get up. Place feed and water where it can be reached easily without having to move any more than necessary. Be extremely careful about movement while using NSAIDs (bute, banamine, previcox, etc.) as it masks pain and encourages more movement than these fragile feet are actually able to withstand. Additionally, NSAIDs (and icing) do not work on metabolic laminitis and long term NSAID use interferes with healing. Therefore, we recommend tapering off NSAIDs after the first week or so of use. If after a week's time your equine's comfort level has not increased, then the cause of the laminitis has not been removed and keeping up the NSAIDs isn't the answer - you need to address the underlying cause.
There is lots more information in our files and archived messages and also on our website. It is a lot of information, so take some time to go over it and feel free to ask any questions. If you are feeling overwhelmed, don't worry, you will catch on, and we are always here to help you! Once you have your case history uploaded, we can help you help your equine partner even better. For members outside North America, there are country specific folders in the files and many international lists in the wiki to help you find local resources. If you have any technical difficulties, please let us know so we can help you. -- Cindy and Glow - Sep 2017, Singapore
ECIR Primary Response Case History: https://ecir.groups.io/g/CaseHistory/files/Cindy%20and%20Glow
Photos: https://ecir.groups.io/g/CaseHistory/album?id=9798
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