MUFFY. - ATTN.: NANCY COLLINS
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martha williams
Dear Nancy,
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Hi MarthaHere's a link to our previous conversation about resveratrol
Equine Cushings and Insulin Resistance
Some studies on pubmed show resveratrol as possibly helping ulcers in humans. I took only a quick look but the cortisol rise would not be good. What would be the reason for a TRH stim if her ATCH has already shown her as PPID in prior testing? To see if the PPID is controlled? This is from a post earlier this summer: A new study from Spain found the TRH stimulation can yield a false positive during the seasonal rise in ACTH. https://groups.yahoo.com/neo/groups/EquineCushings/conversations/messages/187457 Influence of feeding status, time of ... [Domest Anim Endocrinol. 2014] - PubMed - NCBI Here's more info on TRH stimulation. Equine Cushings and Insulin Resistance
Nancy C in NH ECIR Moderator 2003 Learn the facts about IR, PPID, equine nutrition, exercise and the foot. www.ECIRhorse.org Check out the FACTS on Facebook https://www.facebook.com/ECIRGroup Support the ECIR Group Inc., the nonprofit arm of the ECIR Group Equine Cushing's and Insulin Resistance Group Inc.
---In EquineCushings@..., <mjwd444@...> wrote : Dear Nancy,
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martha williams
Hi Nancy Hi MarthaHere's a link to our previous conversation about resveratrol
Some studies on pubmed show resveratrol as possibly helping ulcers in humans. I took only a quick look but the cortisol rise would not be good. What would be the reason for a TRH stim if her ATCH has already shown her as PPID in prior testing? To see if the PPID is controlled? This is from a post earlier this summer: A new study from Spain found the TRH stimulation can yield a false positive during the seasonal rise in ACTH. https://groups.yahoo.com/neo/groups/EquineCushings/conversations/messages/187457 Influence of feeding status, time of ... [Domest Anim Endocrinol. 2014] - PubMed - NCBI
Here's more info on TRH stimulation. Equine Cushings and Insulin Resistance
Nancy C in NH ECIR Moderator 2003 Learn the facts about IR, PPID, equine nutrition, exercise and the foot. www.ECIRhorse.org Check out the FACTS on Facebook https://www.facebook.com/ECIRGroup Support the ECIR Group Inc., the nonprofit arm of the ECIR Group Equine Cushing's and Insulin Resistance Group Inc.
---In EquineCushings@..., <mjwd444@...> wrote : Dear Nancy,
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Hi Martha What does ACTH "seems controlled" mean? When was her last test? What dose was/is she on? As has been stated before, we need a case history so we can review your situation when you come to the list with questions.
Nancy C in NH ECIR Moderator 2003 Learn the facts about IR, PPID, equine nutrition, exercise and the foot. www.ECIRhorse.org Check out the FACTS on Facebook https://www.facebook.com/ECIRGroup Support the ECIR Group Inc., the nonprofit arm of the ECIR Group Equine Cushing's and Insulin Resistance Group Inc.
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martha williams
Hello Nancy! But another one was done this AM & the ACTH is way out of control. Muffpuff has begun to improve in terms of her comfort but still has digital pulse in 4 feet. She has been under STRESS. - Maybe They want to give resveratrol, even though it causes rise in I want, for the sake of everyone out there, to post a vigorous
Hi Martha What does ACTH "seems controlled" mean? When was her last test? What dose was/is she on? As has been stated before, we need a case history so we can review your situation when you come to the list with questions.
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As always, thank you LeeAnne for your help on this.What is the link to the CASE HISTORY please?
From the beginning almost 15 years ago, this group has counseled owners to get off the bute asap because of the very thing you have experienced. A quick review of the archived messages by searching on NSAIDS will reveal just how often this has been brought up. To go back to the previous posts, resveratrol is not advised. It makes no sense to me with resveratrol raising cortisol in a horse with uncontrolled PPID. Please read this page on PPID Physiology of PPID
Which says in part: Cortisol production is elevated in PPID horses largely due to ACTH and can induce a degree of insulin resistance. Pergolide is the gold standard for controlling PPID. Getting it under control is critical IMO, based on what you are saying about her laminitis situation. It sounds like she is being hit from two assaults. You will get far more help for this horse by raising your pergolide dose. You can contact the pharmacy and ask them to share what their testing has shown. At least one member has done side-by-side testing and found their compounded retained efficacy. The FlLES have a copy of the testing done by UC Davis that shows 98% efficacy after 30 days for tablets or powder from a reliable pharmacy. She needs to have her trim right on the money as well. Please, for the sake of this mare, take control of the situation. It needs to be done now. You are her advocate. She is relying on you. Nancy C in NH ECIR Moderator 2003 Learn the facts about IR, PPID, equine nutrition, exercise and the foot. www.ECIRhorse.org Check out the FACTS on Facebook https://www.facebook.com/ECIRGroup Support the ECIR Group Inc., the nonprofit arm of the ECIR Group Equine Cushing's and Insulin Resistance Group Inc.
---In EquineCushings@..., <mjwd444@...> wrote : Hello Nancy!
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ThePitchforkPrincess@...
HI Nancy and Martha,
The Link to the Case History is Martha, You'll want to post the above link , with the rest of your signature every time you ask about Muffy. -LeeAnne, 03/04 Newmarket, Ontario ECIR Archivist http://TakenForGraniteArt.webs.com Are you in the Pergolide Dosage Database? http://tinyurl.com/m6syzt4 ECIR Files Table of Contents: http://tinyurl.com/pfk9m4l
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