1. ECIR | Main
  2. Topics

Pergolide versus Pergolide mesylate

Eleanor Kellon, VMD
 

This is the response from BI:

"Thank you for contacting Boehringer Ingelheim Veterinary Technical Services. You raised a very good question that, frankly, took a few days to circulate and find the answer.

 

The brief answer is, Prascend is the same worldwide. So, as you identified, the language is different from US & UK. No matter US or UK, there is 1.3 mg of pergolide mesylate (the salt) and once metabolized, 1 mg of pergolide.

 

So, to answer your question below, 1 tablet contains 1 mg of actual pergolide (1.3 mg of pergolide mesylate).

 

Let us know if you have further questions.

 

Best regards,

 

Kerby Weaver, DVM

Technical Service Veterinarian

A Boehringer Ingelheim Vetmedica Inc."

So, to equal a 1 mg tablet of Prascend need 1.3 mg of pergolide mesylate.

Eleanor in PA
www.drkellon.com
EC Co-owner
Feb 2001


Cass in NorCal
 

May I forward this post to the pharmacist at Thriving Pets? I tried to report the jist to him, and he's very interested in getting to the bottom of this issue.

Cass for Satra (from 9 Prascend to 9 mg compounded pergolide)
Sonoma County, Calif Oct. '12

Lisa S
 

Dr. Kellon,

Thank you so much for checking on the pergolide-vs-pergolide mesylate question. 

So, for clarity's sake, when a veterinarian is writing a script for pergolide, and he wants to insure that the amount given will be, shall we say for example, .5 mg, what is the best way for that script to be worded?

If it is written as '.5 mg pergolide' is that clear enough to insure that the final product will contain .5 mg pergolide? It seems that there might not be complete clarity on this issue among all the compounders, so just trying to insure that the dosage that is being scripted is actually being compounded, and that there is not confusion.

Thanks!

Lisa in TX
Zippy, Rita and Bunny - IR
June 2010

Eleanor Kellon, VMD
 


---In EquineCushings@..., <mostlyaggies@...> wrote :

So, for clarity's sake, when a veterinarian is writing a script for pergolide, and he wants to insure that the amount given will be, shall we say for example, .5 mg, what is the best way for that script to be worded?

= = = = = = = =

0.5 mg of actual pergolide from pergolide mesylate - i.e, 0.655 mg of pergolide mesylate.

Eleanor in PA
www.drkellon.com
EC Co-owner
Feb 2001

1 - 4 of 4