Amount of pergolide in compounded capsules vs Prascend


Hi, all - I know this is an area of some confusion.  Prascend tablets contain 1 mg of pergolide as pergolide mesylate. 

When switching to or from Prascend, make sure to get the vet to write the script as "x mg of pergolide as pergolide mesylate" ,  rather than "x mg of pergolide"  That way, each capsule will have the same amount of pergolide as the equivalent number of Prascend tablets. So, a prescription for 2 mg of pergolide as pergolide mesylate will contain the same amount of pergolide (and pergolide mesylate) as 2 Prascend tablets.

If you are already on compounded pergolide, and are increasing the dose, there is no need to fuss about whether the pharmacy has given you x mg of pergolide, or x mg of pergolide mesylate, because you are titrating the dose up until you get control of the ACTH. It doesn't really matter what form it is in.

Does that make sense?. 
Jaini Clougher (BSc, BVSc)
Merlin (over the bridge), Maggie, Gypsy, Ranger
BC 09
ECIR mod/support .,,,20,1,0,0 .

Nancy C

More reading at #pergolidestrength

Nancy C in NH
ECIR Moderator 2003
DDT+E = effective treatment for PPID and EMS/IR equines: