Date
1 - 9 of 9
Transitioning from prascend to compounded pergolide
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Could some one point me to the information on the above topic? Namely how the prescription should be written to assure the same dosage is being given?
Currently Jewel is on one mg of Prascend. Thank you -- Cheryl and Jewel Oct 2018 Port Alberni BC Canada https://ecir.groups.io/g/CaseHistory/files/Cheryl%20and%20Jewel https://ecir.groups.io/g/CaseHistory/album?id=81063
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Cheryl here is a link to a message with helpful info and links to more messages. https://ecir.groups.io/g/main/message/244830?p=,,,20,0,0,0::Created,,compounded+pergolide,20,2,0,69241073
When you first want more info about a subject please start by doing a search of the messages. There is a search block at the top of every page (see the top of this page) so just type something like "ordering compounded pergolide". Also we have excellent "Files" see the link to our files in the column on the left side of the Main Group page. If you open the files you will find the search box at the top of the page. -- Bonnie Snodgrass 07-2016 ECIR Group Primary Response White Cloud, Michigan, USA
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Deb Walker
I started Scotty with a liquid compounded Pergolide, and after nearly a year of not seeing a lot, discovered that was probably a mistake. There are a lot of files here, including some of mine, that state how the liquid compounded versions do not hold their potency. Who would have known? I have since informed my vet. We now use Pet Health Pharmacy and he is getting 4 mg pergolide which actually equals about 3 mg Prascend, and he is doing well. I get the capsules, and after trial and error making sure they are consumed, I just stick one way back in the corner of his cheek, hold my hands over his face/teeth, and wait for it to go down. Otherwise, he got so he wouldn't even take a treat from me because I had meds mixed in.
-- Deb and Scotty I/R, PPID Pecatonica Illinois, May 13, 2019 Case History: https://ecir.groups.io/g/CaseHistory/files/Deb%20and%20Scotty Photos: https://ecir.groups.io/g/CaseHistory/album?id=90619
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Hi, I just recently switched from Prescend to Compounded Pergolide from Wedgewood Pharmacy. I haven’t started it yet. RC is on 2 mg of Prescend daily. I assumed he would get the same dose of Pergolide. Am I wrong?
On a different note, RC has started sweating under his sheet this year. We have been taking them off at night and putting it on during the day as needed. He has a full body clip, minus the legs and neck, which doesn’t seem to be helping. My vet suggested adding Cyproheptadine, which he has been on for 2 weeks with no change. She suggested repeating his bloodwork in March. Is there anything else I can do?? Any suggestions on blankets that whisk moisture away? I don’t want him to get chilled. Thank you all!! -- Jan and RC Stockertown, PA, USA Feb 2018 RC Case History ( https://ecir.groups.io/g/CaseHistory/files/Jan%20and%20RC ) RC Photos ( https://ecir.groups.io/g/CaseHistory/album?id=42022&p=pcreated,,,50,2,0,0 )
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Hi Jan
Try this link for info on pergolide dosage when switching. There is specific language your vat should know. https://ecir.groups.io/g/main/topic/3760540?p=,,,100,0,0,0::Created,,%23pergolidestrength,100,2,0,3760540,ct=1&ct=1 Additionally lots more information in the HASHTAG section. See collection of messages on pergolide strength https://ecir.groups.io/g/main/hashtags Cyproheptadine as an addition to pergolide is not effective. There is no support for it's use as effective in the veterinary literature, except from the maker of Prascend. They needed to give folks a place to go beyond the expense of their drug. Most of us switched to compound instead when this happened, because the cypro does not work. I am not aware, could not find info relating to cypro and sweating. https://ecir.groups.io/g/main/message/189773?p=,,,100,0,0,0::Created,,posterid%3A58231+cyproheptadine,100,2,0,1060672 He may need a dosage increase. Testing will let you know. -- Nancy C in NH ECIR Moderator 2003 ECIR Group Inc. President/Treasurer 2019-2020 Join us at the 2020 NO Laminitis! Conference, October 22 - 25, Harrisburg, PA
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Hi Jan,
Here is an old post from Jaini,discussing exactly this:
Lorna in Eastern Ontario
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Sherry Morse
Hi Jan, How did your vet send the prescription in to Wedgewood? If it was written as 2mg of pergolide as pergolide mesylate it's equivalent to 2 Prascend. If it was not written that way it will be less. You can reference this post: Amount of pergolide in compounded capsules vs Prascend as well as this one: Re: Switching from Prascend to CP As far as the sweating - that may be an indication that his PPID isn't as controlled as it should be so I would suggest bloodwork now rather than waiting until March and adjusting his dose of pergolide accordingly. Cyproheptadine is an old treatment for PPID and from what I've read not a very reliable one. You can read one study on it comparing it to using pergolide here: Treatment with Pergolide or Cyproheptadine of Pituitary Pars Intermedia Dysfunction (Equine Cushing's Disease)
Thanks, Sherry and Scutch (and Scarlet over the bridge) EC Primary Response PA 2014 https://ecir.groups.io/g/CaseHistory/files/Sherry%20and%20Scutch_Scarlet https://ecir.groups.io/g/CaseHistory/album?id=78891
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I would like to emphasize here that there is not one shred of new evidence to show that cyproheptadine is useful in PPID. It was resurrected to give vets already using the top recommended dose of Prascend but without success something else to do.
-- Eleanor in PA www.drkellon.com 2 for 1 course sale
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Thank you both!! I appreciate the information.
-- Jan and RC Stockertown, PA, USA Feb 2018 RC Case History ( https://ecir.groups.io/g/CaseHistory/files/Jan%20and%20RC ) RC Photos ( https://ecir.groups.io/g/CaseHistory/album?id=42022&p=pcreated,,,50,2,0,0 )
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