Giving Invokana
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Gymah
What is the best way to give Invokana? Can it be crushed and given in a syringe? Is it caustic like Metformin/ does milk of magnesia have to be used as a carrier?
-- Helene A. in BC 2021 Photo album: https://ecir.groups.io/g/CaseHistory/album?id=271068 Case history: https://ecir.groups.io/g/CaseHistory/files/Helene%20and%20Rosie
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Helene, did you and your veterinarian get the critical background information from Dr Kellon?
-- Cass, Sonoma Co., CA 2012 ECIR Group Moderator Cayuse and Diamond Case History Folder Cayuse Photos Diamond Photos
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Gymah
Yes
-- Helene A. in BC 2021 Photo album: https://ecir.groups.io/g/CaseHistory/album?id=271068 Case history: https://ecir.groups.io/g/CaseHistory/files/Helene%20and%20Rosie
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Thanks for putting my mind at ease. My mare eats her Invokana tablet easily in a small handful of supplement. I haven’t had a single rejection. I snap the whole tablet in half so it’s basically the same size as the supplement. I know you don’t have access to Stabul1, but that’s what I use to hand feed any medication.
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Flame eats it in a small handful of his treats. I alternate between unsalted pumpkin seeds, sliced almonds & split green peas. I just put the pill & his Pergolide capsule on the top of the small handful & he gobbled it right down.
-- Beth & Flame dx 2013 & Diana dx 2020 NV Oct 2013 Flame Pictures
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Gymah
Is it typically only given once a day, or is splitting the dose to give twice a day better?
-- Helene A. in BC 2021 Photo album: https://ecir.groups.io/g/CaseHistory/album?id=271068 Case history: https://ecir.groups.io/g/CaseHistory/files/Helene%20and%20Rosie
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Gymah
Does it matter if it’s given at the same time as Prascend?
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Helene,
No problem with giving with Prascend and if syringe works best for you that's OK too. -- Eleanor in PA www.drkellon.com
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Gymah
My pony is currently on Metformin (with uncontrolled insulin). I've been waiting on the blood results to see about starting Invokana, and unfortunately they just came back with a high triglyceride result (I don't know the exact number - waiting on the test to be sent over to me). Because of this my vet doesn't want to start her on Invokana for fear of causing liver and/or kidney damage (apparently he talked to a vet who is involved in a clinical trial with Invokana in horses, and he recommended that my pony not have Invokana as well).
Definitely disappointing -- Helene A. in BC 2021 Photo album: https://ecir.groups.io/g/CaseHistory/album?id=271068 Case history: https://ecir.groups.io/g/CaseHistory/files/Helene%20and%20Rosie
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We can help you try to get the triglycerides down. What is the current diet? Have you see the posts about L-carnitine?
-- Eleanor in PA www.drkellon.com
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Also read this study and send it to your vet https://pubmed.ncbi.nlm.nih.gov/23663085/ .
-- Eleanor in PA www.drkellon.com
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Gymah
Soaked Timothy (hay analysis is in my photo album). She gets 3 flakes a day in a hay net (not sure on lbs). She also gets 1.5 cups (before soaking) of the Ontario dehydrated timothy balance cubes with flax, J-herb, and MadBarn Aminotrace. She doesn't really like this though (she has never been a fan of beetpulp or hay cubes), so sometimes she eats it, and sometimes she doesn't, or she'll just eat some of it.
She's a really good weight (with ribs slightly visible and the fat pads on her rump are gone, and the ones on her shoulders are getting smaller. I think her crest is maybe even starting to get a bit smaller too). I doubt she'll eat L-carnitine. She's a picky eater and its hard to get her to eat anything consistently (unless it's really high in starch/ sugar). -- Helene A. in BC 2021 Photo album: https://ecir.groups.io/g/CaseHistory/album?id=271068 Case history: https://ecir.groups.io/g/CaseHistory/files/Helene%20and%20Rosie
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OK. Need you to actually weigh what she is getting. If you can't get the carnitine into her you could always syringe it.
-- Eleanor in PA www.drkellon.com
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I'm not sure if this information is still current but if you can get soy hulls that will solve your palatability problem https://ecir.groups.io/g/main/files/9d%20Country%20Specific%20Information/Canada/Soy%20Hulls.pdf .
-- Eleanor in PA www.drkellon.com
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Gymah
I just got the blood results. Triglycerides are 1.97 mmol/L (reference range 0.09-0.58).
Is this very elevated? -- Helene A. in BC 2021 Photo album: https://ecir.groups.io/g/CaseHistory/album?id=271068 Case history: https://ecir.groups.io/g/CaseHistory/files/Helene%20and%20Rosie
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That is a mild to moderate elevation. I'm sure if they were checked routinely we would find a lot more horses in that category.
-- Eleanor in PA www.drkellon.com
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