Date
1 - 8 of 8
Sunday labs & case history updated - CBD info
|
rozaniloc@...
Hello friends -
I have updated Sunday's case history & labs. Like many here, he has more than one challenge (PPID, IR, melanomas, arthritis). After one year on Prascend his labs looked good last April 2021, but his melanomas were accelerating. So last spring I started giving him cannabis oil (legal here). I gave 5 ml twice a day (it was infused in coconut oil) until this April 2022. He seemed to do well throughout the year. But this year's labs came back with ACTH in the mid 20's (previously low teens) & insulin mildly elevated. After getting these results something percolated in my brain & after a couple weeks I recalled something Dr Kellon had replied to about not using CBD in PPID horses. So we (mostly me, my vet gives me all her knowledge, but is quite willing to listen to what I learn here, so she was concerned when I told her I couldn't remember why, but I thought CBD might be contraindicated with the PPID) decided to give the cannabis oil 12 hrs away from the Prascend & see what blood work would say in a month. Just got those results back & EEK - ACTH is even higher, & insulin the highest it has ever been :( Needless to say, I have stopped the cannabis oil & plan to recheck ACTH/insulin in 3-4 weeks. Any other thoughts or advice if I should do differently? One concern I have is whether in mid-late June we will already be into the fall rise, in case I need to increase his Prascend. Thanks in advance for your thoughts. Rozanne & Sunday July 02 2019 Larimer County, Colorado case history: https://ecir.groups.io/g/CaseHistory/files/Rozanne%20&%20Sunday photos: https://ecir.groups.io/g/CaseHistory/album?id=93586 |
|
|
|
I would definitely increase the pergolide now. That could also help with the melanomas since melanocyte stimulating hormone is also increased in PPID.
-- Eleanor in PA www.drkellon.com |
|
|
|
rozaniloc@...
Thank you Dr Kellon - what amount increase do you recommend? 1/2 tab? 1 whole tab?
-- Rozanne & Sunday July 02 2019 Larimer County, Colorado case history: https://ecir.groups.io/g/CaseHistory/files/Rozanne%20&%20Sunday photos: https://ecir.groups.io/g/CaseHistory/album?id=93586 |
|
|
|
There is not much time for titrating so I would go a full tab, then if he's really low early next year you can back it up a bit.
-- Eleanor in PA www.drkellon.com |
|
|
|
Dr K, I hadn't realized that CBD was contraindicated for PPID, how influential is it and is it recommended to stop it? I have had Vinnie and Summer on CBD for about 2 years. (Ugh)
Also have you considered developing a Grey Horse Defense without CTB and Hemp? I loved that product but stopped because of the CTB. -- Nancy and Vinnie and Summer Oakley, Ca Joined Nov 2018 https://ecir.groups.io/g/CaseHistory/files/Nancy%20and%20Vinnie https://ecir.groups.io/g/CaseHistory/album?id=245855 Summer https://ecir.groups.io/g/CaseHistory/files/Nancy%20and%20Vinnie/Summer https://ecir.groups.io/g/CaseHistory/album?id=249104 |
|
|
|
CTB can bind to dopamine receptors and there is evidence it interferes with pergolide. It could be OK to use for a short period in early Spring when ACTH levels are at their lowest but beyond that I wouldn't use it.
I had no input on development of the Grey Horse Defense products but you could send a mail to Uckele. -- Eleanor in PA www.drkellon.com |
|
|
|
Would you also stop CBD in terms of dopamine?
Thx Nan -- Nancy and Vinnie and Summer Oakley, Ca Joined Nov 2018 https://ecir.groups.io/g/CaseHistory/files/Nancy%20and%20Vinnie https://ecir.groups.io/g/CaseHistory/album?id=245855 Summer https://ecir.groups.io/g/CaseHistory/files/Nancy%20and%20Vinnie/Summer https://ecir.groups.io/g/CaseHistory/album?id=249104 |
|
|
|
|
|
|