Acute Allergic Reaction on Face: Medication help


bectonliterary
 

Hi all,

Darcy had what we believe to be an allergic reaction Wednesday. Here are the vet's notes for reference:
The horse has a extremely swollen face and muzzle mostly on left side which does extend to the right side. The cheeks and lips are very firm and painful to touch. i did not try to open the mouth due to pain elicited when she was resisting just palpation of the oral cavity as far as my fingers could reach . I didnt feel any wounds intra-orally but there was a small scab on the lower mandible which could be from a tiny puncture. There is some lymphadenopathy on bot sides but based on age and her teeth condition that could be from tooth infection.. starting treatment on antibiotics Excede 16 cc given 8 cc in neck each side which need repeat in 4 days. Also give banamine 9 cc twice daily for swelling and Benadryl 60 cc twice daily as needed until at least 75% better. Cold hosing is recommended for 30 minutes twice daily you can use dormosedan gel 1/3 tube under tongue 1 hr prior to help perform hydrotherapy. If no improvement in couple days would go ahead and start Dexamethasone

 

I have cold hosed her 3 times and the swelling is reducing. She has been eating beet pulp mashes and started eating a small amount of soaked hay last night. I'm pretty sure banamine and dex are both not recommended for PPID horses. We haven't given dex yet. Are there other alternatives to help with the reaction? If we give dex, should I temporarily adjust her pergolide dose to help compensate? 

She's on 4 mg compounded pergolide. Her last ACTH test was taken June 13: 24.5 pg/ml (reference interval 2-30). (I haven't updated my medical history yet.)
--
Jennifer and Darcy in SC

October 2011

https://ecir.groups.io/g/CaseHistory/files/Jennifer%20and%20Darcy


Eleanor Kellon, VMD
 

Jennifer,

Banamine is fine short term in a situation like this. It has no interaction with PPID, although the Dormosedan could but you probably don't really need that just to do cold hosing. Dexamethasone should be avoided. In life threatening situations, or when PPID is controlled well, dexamethasone should be used when really needed, at lowest dose possible to avoid laminitis. It sounds like she's on the right track and you won't need dexamethasone. A potential alternative would be topical or IV DMSO.
--
Eleanor in PA

www.drkellon.com 
EC Owner 2001
The first step to wisdom is "I don't know."


bectonliterary
 

Thank you so much, Dr. K. I so appreciate you being here to help us all. Darcy is doing even better this morning. Her swelling continues to lessen and she's increasingly able to eat. 

I will save this thread just in case though. I never expected her to have an allergic reaction like this! 

Again, thank you!
J
--
Jennifer and Darcy in SC

October 2011

https://ecir.groups.io/g/CaseHistory/files/Jennifer%20and%20Darcy


Joy V
 

Hi Jennifer,

FWIW, last Dec my horse had an allergic reaction to some shavings and when I found him, he was swollen all over his body/head and he had hives the size of my hands everywhere.  He was also colicing from being down for too long.  My vet gave him IV benedryl and I was so surprised at how quickly it worked.  I have given my horse oral benedryl many times, but it doesn't work like IV does.  Just for future reference in case of emergency allergy response.  Glad Darcy is doing better this am.  That is good news.  :)

Joy


--
Joy and Willie (EC/IR)
Nevada County, CA - 2019

Case history:  Willie's Case History
Willie's photo album:  Willie's Photos


Eleanor Kellon, VMD
 

Should also mention that because it is primarily one-sided it's likely to be something like a bee sting or insect bite.
--
Eleanor in PA

www.drkellon.com 
EC Owner 2001
The first step to wisdom is "I don't know."