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Seasonal Rise and Pergolide
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Reta Heaslip
Thank you, Sherry, for the unit conversion info and recommendation.
-- Reta Sept 7, 2017 Gananoque, ON, CA https://ecir.groups.io/g/CaseH https://ecir.groups.io/g/CaseHistory/album?id=10035 |
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Sherry Morse
Hi Reta, Both of those upper numbers you are referencing are for normal horses. For PPID horses we want to keep their ACTH level in the upper teens/low 20s (in pg/ml terms) year round. 8.9pmol/L translates to 40.4pg/ml as per Adrenocorticotropic hormone (ACTH) conversion to pmol/L, pg/mL, pg/dL, pg/100mL, pg%, pg/L, ng/L . Online converter from conventional units to SI units | UNITSLAB.COM which means Whistler is due for a dose increase. Were he mine I'd look at bumping him up a full mg to try to get his level down.
Thanks, Sherry and Scutch (and Scarlet over the bridge) EC Primary Response PA 2014 https://ecir.groups.io/g/CaseHistory/files/Sherry%20and%20Scutch_Scarlet https://ecir.groups.io/g/CaseHistory/album?id=78891 |
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Reta Heaslip
Thank you Lorna. Correction...Whistler has been on 3 mg Pergolide since September 27, 2019.
-- Reta Sept 7, 2017 Gananoque, ON, CA https://ecir.groups.io/g/CaseH https://ecir.groups.io/g/CaseHistory/album?id=10035 |
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Reta Heaslip
Blood was drawn on August 22, 2022 to test ACTH level for Whistler. The test result from IDEXX came back as 8.9 pmol/L (ref. range 2.0 - 10.0 pmol/L). In doing research on ECIR site for acceptable level of ACTH during seasonal rise, I came across differing numbers. For example, one message said ACTH levels should be in the low 20's pg/ml (Cornell) year round whereas another message stated an acceptable level of ACTH during seasonal rise as 49 pg/ml (Cornell) and up to 29 pg/ml (Cornell) for the rest of the year. What does ECIR recommend as safe levels of ACTH for both Cornell and IDEXX based on their ref. ranges? Also is there a simple method for converting pmol/L to / from pg/ml?
Whistler has been on 3 mg of Pergolide since September 27, 2022. From mid July 2022 he has shown a marked decrease in topline, and, ribs, hips and points of buttock are quite noticeable.. Should I increase his Pergolide now and, if so, by how much and for how long? Looking forward to information and direction. -- Reta Sept 7, 2017 Gananoque, ON, CA https://ecir.groups.io/g/CaseH https://ecir.groups.io/g/CaseHistory/album?id=10035 |
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